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Senin, 13 April 2009
New Drug May Help Patients With Psoriatic Arthritis
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THURSDAY, April 9 (HealthDay News) — The drug golimumab shows promise in treating psoriatic arthritis, according to a new study. Psoriatic arthritis affects about 11 percent of people with psoriasis.
The University of California, San Diego-led study included 405 patients who still had active psoriatic arthritis after taking anti-rheumatic drugs or nonsteroidal anti-inflammatory drugs. The patients were randomly selected to receive injections of either 50 or 100 milligrams of golimumab or placebo every four weeks for 24 weeks.
The phase 3 study found that 51 percent of patients in the 50-mg group, 45 percent of those in the 100-mg group, and 9 percent of those in the placebo group achieved the American College of Rheumatology 20 percent improvement criteria (ACR20) by week 14. The improvements were in areas such as swollen and tender joints, pain, disease activity, physical function, and levels of C-reactive protein.
The University of California, San Diego-led study included 405 patients who still had active psoriatic arthritis after taking anti-rheumatic drugs or nonsteroidal anti-inflammatory drugs. The patients were randomly selected to receive injections of either 50 or 100 milligrams of golimumab or placebo every four weeks for 24 weeks.
The phase 3 study found that 51 percent of patients in the 50-mg group, 45 percent of those in the 100-mg group, and 9 percent of those in the placebo group achieved the American College of Rheumatology 20 percent improvement criteria (ACR20) by week 14. The improvements were in areas such as swollen and tender joints, pain, disease activity, physical function, and levels of C-reactive protein.
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